We've got an updated package on squamous cell carcinoma. Click here to check it out. The oral cavity is a common site for neoplasia in cats. Squamous cell carcinoma (SCC) is the most common oral malignancy in the cat, arising from either the jaw bones or the tongue. Squamous cell carcinoma is an. A squamous cell carcinoma is a type of cancer that originates in the squamous epithelium. It may appear to be a white plaque, or a raised bump on the skin.
in What Cats? Carcinoma is Squamous Cell
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Snail Bait Poisoning in Dogs. Toxic and Non-toxic Plants. The final diagnostic step, which is done under short anesthesia, is a large incisional biopsy. Biopsy is preferred over cytology or aspirates to definitively differentiate between benign noncancerous and malignant cancerous tumors and determine the exact type of tumor present.
This is important in order to plan appropriate treatment that will best maximize the cat's response to therapy and survival.
Routine bloodwork is usually recommended to make sure the cat is in good overall health otherwise prior to anesthesia and biopsy. What are the treatment options for oral squamous cell carcinoma in cats? Surgery Surgical removal of the tumor is the fastest and most likely curative option for localized tumors that have not yet spread to other organs.
Therefore, surgery is usually the first treatment option whenever possible. Because these tumors are very aggressive and invade deeply into the bone and other structures in the mouth, it is usually recommended to perform an aggressive surgery, which may affect the cosmetic and functional appearance of the cat. For these cats, other options exist such as radiation therapy or chemotherapy but only achieve little and short-lived success as described below.
Radiation therapy Radiation therapy is a type of treatment that uses penetrating beams of high energy waves gamma rays or streams of particles generated by linear accelerators that kill cancer cells by damaging their DNA. Radiation therapy alone intended for palliative reasons aiming at providing relief rather than curative reasons is not typically recommended for cats with oral SCC due to the expected poor tumor control and risk of adverse effects.
The side effects of radiation therapy can include hair loss, inflammation of the oral cavity, difficulty swallowing, or eye changes. To learn more about this treatment, please visit the Radiation Therapy section. The use of radiosensitizers drugs that make cancer cells more sensitive to radiation is a new way to try to improve the cat's response to radiation therapy. In a study of eight cats that were treated with combination of gemcitabine a chemotherapy drug and palliative radiation, two cats achieved complete response, four cats achieved partial response and two cats had no response.
In these cats, median survival time was In another study with nine cats, using a radiosensitizer called etanidazole resulted in partial responses in all nine cats and median survival was days. Chemotherapy There is no known effective chemotherapy drug to treat oral SCC in cats. Several chemotherapy drugs have been evaluated in cats with oral SCC but in most cases, they only 'buy' some time rather than producing durable and meaningful response. What is the prognosis for cats with oral squamous cell carcinoma?
Oral SCC is a very aggressive disease and there is no known effective treatment. The quality of life for the cats rapidly deteriorates and most cats are euthanized due to their inability to eat and drink within three months of diagnosis. Home What is a Veterinary Specialist? What is a Board Certified Veterinary Specialist? Oncology , Veterinary Specialists. Pacemaker Therapy March 20, Find a Veterinary Specialist. What to expect at a Specialist.
SQUAMOUS CELL CARCINOMA
Rather, the veterinarian is searching for tiny, scabby sores on the cat's skin that could indicate the presence of squamous cell carcinoma (SCC) — a skin cancer . Skin changes should never be ignored in your cat. Learn how and aggressive type of cancer can run rampant if left unchecked. Overview. Squamous cell carcinoma (SCC) is the most common oral tumor in cats and typically affects middle-aged to older cats. Factors that may increase the .