Of the cannabinoids so far identified, cannabidiol (CBD) is among the most exciting because of its antioxidant and neuroprotective properties. We will emphasize the neuroprotective, antiinflammatory, and . Unlike the psychoactive properties associated with Δ9-THC, CBD has been. The neuroprotective properties of CBD do not appear to be exerted by the activation of key targets within the endocannabinoid system for plant-derived.
CBD Neuroprotective Properties of
Of the cannabinoids so far identified, cannabidiol CBD is among the most exciting because of its antioxidant and neuroprotective properties. A patent by the U. National Institutes of Health even acknowledges these therapeutic benefits and potential uses of CBD. Antioxidants are an important part of any nutritious diet and are essential for maintaining health and proper biological function.
An antioxidant is a natural substance that inhibits oxidation, a chemical reaction that produces the free radicals that eventually damage cells and lead to illnesses and chronic diseases. Antioxidants are able to neutralize these damaging oxidizing agents from the bloodstream to improve the health of cells and reduce the risk of developing a disease.
The body naturally produces antioxidants, but the amounts are often insufficient for neutralizing all of the harmful effects of oxidative stress. These can take several weeks to make improvements, whereas CBD starts combatting depression after the first dose and remains an effective treatment with consistent use.
The huge helmets worn by NFL players only offer limited protection to athletes in this most physical of sports. Some players have experienced life-long brain damage from injuries they have picked up on the field. Famous cannabis advocate, psychiatrist and Professor emeritus at Harvard University Dr Lester Grinspoon, believes that the NFL needs to look more closely at medical marijuana as a means to protect their players.
Cannabinoids have been likened to internal shock absorbers, in that they can sap up the force of a head trauma-inducing blow, limiting the neurological damage dealt. Research suggests that a high-CBD, low-THC cannabinoid profile could be the most effective way of using cannabis medicine for neuroprotective purposes. A good mixture of terpenes and other cannabis chemicals helps to enhance the effects of CBD and other neuroprotective cannabinoids.
Grinspoon also informed the NFL that players could be given a cannabis formula which produces no psychoactive effects.
Compared to the current plethora of opioid painkillers that athletes are prescribed, changing to medical cannabis would seem a no-brainer. But for that, governments will need to drop the restrictions which prevent extensive research of the herb. Your email address will not be published. FREE shipping is back! Marijuana and minor traumatic brain injuries The research into cannabis and traumatic brain injuries is incredibly promising.
Treating post-concussion syndrome with marijuana Sometimes, post-concussion syndrome PCS occurs after a concussion. While some may not want the euphoria associated with THC and other euphorogenic constituents of the plant, there is the therapeutic consideration of the benefit of using the whole plant the entourage effect. As with any therapeutic agent the physician will weigh the balance of the therapeutic effects to the side effects. Many clinicians believe that using CBD as an isolated compound not only diminishes its therapeutic value but does not take full advantage of the medicinal value of cannabis.
This is because of the entourage effect, the concept that the totality of the therapeutic constituents of the plant acting together are more effective than any single isolated compound acting alone. Cannabis contains several hundred compounds, including various flavonoids, aromatic terpenes, and many minor cannabinoids in addition to THC and CBD. When looking at the effects of cannabis we need to be cognizant that different routes of cannabinoid administration have different effects.
Inhaled THC enters capillaries in the lungs, passes into general circulation through the pulmonary arteries and goes directly to the brain without passing through the liver. The cannabinoids then cross the blood-brain barrier to affect the endocannabinoid receptors. In addition, when cannabis is burned new compounds are created not found in the raw or dried plant. The respiratory route of administration allows THC and other constituents of the plant to go directly to the brain without going through the liver.
THC metabolites contribute significantly to the effects of cannabis consumption. It induces a high more potently than THC itself. When ingested orally, however, THC and other cannabinoids and terpenes are absorbed from the small intestine over several hours. Like any oral medication, it will take about minutes before enough of the plant constituents are in the bloodstream to exert a therapeutic effect.
All plants are chemically complex, containing hundreds of different molecules. A tomato has about different molecules. Of these compounds, are cannabinoids and over are terpenes.
Many of these chemicals have therapeutic value. The ECS is the largest neurotransmitter system in the brain. It can be affected by both exogenous from outside the body and endogenous from inside the body cannabinoids that exert their many pharmacological effects. There are at least two types of cannabinoid receptors in mammalian tissues, dubbed CB1 and CB2 receptors. CB1 receptors are not only in the brain and spinal cord but in peripheral tissues as well.
CB2 receptors are found primarily in immune tissues. It is quite likely that in the near future, research will identify more components of the ECS.
A Primer About Cannabidiol And The Benefits Of CBD
Ann N Y Acad Sci. ; Neuroprotective antioxidants from marijuana. Hampson AJ(1), Grimaldi M, Lolic M, Wink D, Rosenthal R, Axelrod J. Science keeps proving cannabinoids have antioxidant and neuroprotective properties. Lab research has shown promising results for CBD as a. Recently Scythian Biosciences announced their positive preclinical data on the efficacy of cannabis for a mild to moderate traumatic brain injury.