Health & Science Perspective CBD, or cannabidiol, is most commonly extracted from hemp, but it can I'd say hype, hope and big bucks. MONDAY, May 7, (HealthDay News) -- Cannabidiol (CBD) oil "There's no control, so it's basically how do you know if we're dealing with the true effect of. The cream Jean used contained cannabidiol, or CBD, one of the chemical From the DEA's perspective, CBD is only legal when used for.
Is the hype CBD, about real? cannabidiol, Perspective or |
For starters, CBD is short for cannabidiol pronunciation here and is one of over cannabinoids which can be extracted from the cannabis plant . CB1 and CB2 . One of the reasons that elucidating the effects of cannabinoids has proven difficult is that the CB1 receptor seems to be found essentially everywhere in the central nervous system the CB2 receptor is mostly found in immune cells.
Importantly, this signal can only travel in one direction; Neuron B typically has to just sit there and listen to whatever Neuron A is saying without responding. Except, that is, in cells equipped with endocannabinoid receptors such as CB1. While the body makes its own molecules that bind with the CB1 cannabinoid receptor, THC binds to this receptor as well and has a similar effect, i. The truth is, we know very little about the effects of cannabinoids, and even less about the action of CBD than we do THC.
So why the explosion in popularity of CBD in the homeopathic sector? This can likely be traced to a rare form of pediatric epilepsy known as Dravet syndrome. A small community of parents in found that oil extracted from marijuana plants low in THC had miraculous effects on children otherwise unresponsive to medication and doomed to 10s to s of seizures a week .
While the evidence was at first anecdotal, in a phase III clinical trial measuring the effectiveness of CBD in treating Dravet syndrome was successful, leading to the first FDA-approved cannabis-derived drug, Epidiolex . This means they have no currently accepted medical use. In theory, this implies they are as dangerous as heroin and more dangerous than meth and fentanyl both schedule II drugs.
Only CBD products derived from the leaves or stems of the hemp plant not the flowers and without the smallest trace of THC are federally legal. While the federal government has mostly turned a blind eye to what is done within states, interstate transport of the cannabinoid is illegal, potentially making access difficult for those in remote areas.
Partially as a consequence of this restriction, CBD research has been slow. A quick poll of the scientific literature turned up 17, studies featuring CBD in While that might seem like a lot, there were more than 4 times as many studies featuring coffee over the same time period. This dearth of research has left a vacuum which has been happily filled with YouTube doctors who joyfully tout CBD as the panacea.
While CBD has clearly shown promise with certain forms of epilepsy, how does it pan out in treating other ailments like pain, anxiety, and cancer? These studies found significant improvements in reported pain and quality of life metrics relative to a placebo group. It would follow that CBD might also work for other types of anxiety such as that associated with public speaking or general social situations. While some preliminary work shows positive results, these studies were exploratory, had low sample sizes, and in one case for some unknown reason only surveyed 10 right-handed men [11,12].
Larger studies more indicative of the general population are needed before any real inferences can be made here.
While CBD and marijuana in general have an established history in reducing the symptoms tied to cancer treatment, such as loss of appetite, there is much less known about the actual effects of the molecule on tumors themselves. Some have suggested that CBD might be a good candidate as an anti-cancer drug , with in vitro studies those conducted in a petri dish showing it may fight the spread of lung cancer .
However, as has been seen time and time again, early success in vitro rarely translates to in vivo success studies conducted in living organisms , and there is no reason to assume that CBD will fare differently from other potential cancer drugs that made it to this point.
Looking forward, CBD has potential to be a useful therapeutic for pain and possibly a host of other ailments. For now, due to the limited research into CBD, we have far more questions than answers. The absence of scientific evidence to support or refute their claims has allowed CBD manufacturers to tell their own narrative to a receptive audience. On the bright side, CBD does not show any signs of being dangerous  as long as what you consume is actually CBD.
Consumer reports suggests verifying a supplier has a certificate of analysis indicating the content of the final product and ensuring the product you buy has the CBD and THC content you desire .
While there is a lot of excitement and potential for CBD as a therapeutic, this largely stems from its youth in the collective consciousness. With time, scientific inquiry will uncover what is true and what is hype. Notably, the chief source of evidence for many of the reports seen in online forums or at farmers markets is anecdotal. While personal accounts are important, without an understanding of variability across individuals, as well as the effects of expectation itself, no individual can act as a deciding data point.
When it comes to any health craze, it is probably best to let the science catch up to the hype. Evolution of the cannabinoid and terpene content during the growth of Cannabis sativa plants from different chemotypes. Journal of natural products, 79 2 , The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: We grow these to make cloth canvas cloth; guess how it got its name or paper. Others are bred to yield heavy, oil-rich seeds. Still others are bred to be rich in a compound called THC tetrahydrocannabinol.
And finally, there are strains bred to be rich in CBD. We now understand that CBD can improve how we feel — sometimes profoundly. In other words, it can bring you back from the brink to a healthy baseline. But a healthy baseline is where it stops. And at reasonable doses, with occasional use, that 0. However, regular use at higher doses, with more sensitive drug tests, could in theory be a problem. There are three delivery systems for CBD: Most people will use oral CBD , which works throughout the whole body.
There are plenty of oral delivery systems to choose from: On your knuckles for painful swollen joints. Over the bottoms of the feet for plantar fasciitis.
Over the lower abdomen for menstrual cramps. I have heard it claimed that some topical CBD gets into the bloodstream and works systemically. Vaporized CBD is the fastest acting, your best bet for situations that need to be addressed quickly. Quickly, as in 15 seconds. Think panic attacks, and breakthrough pain. Honestly, we had to pause a bit before bringing vapes into our store.
But mostly because of how helpful the vape has been to two of our staff members. The vape has been instrumental, I can use it, calm myself back down, do my breathing exercises, do my behavioral type things, get myself back in my body, and stave it off.
Versus when I take the tincture or a capsule, I can feel the leading edges of it an about a half-hour. I still use oral CBD twice a day for my immune disorder pain.
Cannabis: a mind-blowing source of inspiration (for scientists...)
Cannabidiol, better known as CBD, has exploded onto the health and to reduce inflammation and anxiety disorders, the CBD wave is real and it's I know what's reasonable and I can apply that perspective to CBD and the. You can vape CBD, eat CBD cookies, and drink CBD lattes, but does it really do anything? The super-popular cannabis compound, explained. . From a medical perspective, it's promising; recreationally, it's interesting. opposed to those of THC including relief from anxiety, stress, and hyper-excitability. 4 days ago For starters, CBD is short for cannabidiol (pronunciation here) and is one of From the Drug Enforcement Agency's (DEA) perspective, almost all CBD With time, scientific inquiry will uncover what is true and what is hype.