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Elevating By Diminish Sickness Motion

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17.06.2018

Content:

  • Elevating By Diminish Sickness Motion
  • Motion sickness, nausea and thermoregulation: The “toxic” hypothesis
  • Motion Sickness Remedies
  • Motion sickness is a disorder caused by repetitive angular and linear . to reduce motion sickness produced by short arm rotors intended to provide artificial gravity in . are at reduced risk for PONV, whereas nonsmokers have elevated risk. Motion sickness is a common disturbance of the inner ear. Any form of travel can What can I do to prevent or minimize motion sickness? If you know you have. your head elevated about 12 inches above your feet helps reduce nausea. To treat motion sickness in a car, seat your child so that he or she faces the front.

    Elevating By Diminish Sickness Motion

    Symptomatic relief of vertigo can be obtained with anticholinergic agents e. Diazepam mg orally q h is effective in suppressing the vestibular system Table In severe cases, referral to an otolaryngologist is appropriate. Perspiration, increased salivation, yawning and malaise are described by patients with motion sickness. Hyperventilation can lead to hypocapnia, and venous pooling can predispose to hypotension and syncope.

    The sight and smell of food can exacerbate nausea. Motion sickness is readily diagnosed by history. This is a common syndrome that can occur in an automobile, airplane or at sea. Exaggerated self-generated movement, in fact, can cause motion sickness by forcing rapid and inappropriate changes of vestibular function Treatment The treatment of vertigo associated with motion sickness is empirical Transdermal scopolamine can prevent motion sickness.

    The patch must be placed several hours prior to the anticipated onset of motion sickness. Anti-histamines such as dymenhydrinate, meclizine, cyclizine, promethazine and diphenhydramine can be used Table 11 The main side effect of this drug class is drowsiness. Acupressure on the P6 point located on the wrist, which has been used in traditional Chinese medicine to treat nausea and vomiting of pregnancy, has been evaluated in a randomized, placebo-controlled double-blind study.

    Sixty-four subjects were randomly divided into 4 groups P6 acupressure, dummy-point acupressure, sham P6 acupressure, and control and subjected to optokinetic drum rotation which elicits motion sickness in normal volunteers. Subjects in the P6 acupressure group reported significantly less nausea and the incidence of gastric tachyarrhythmia was reduced in this group In another blinded placebo-controlled study on 36 patients, however, acupressure provided no protection These symptoms, suggestive of a viral etiology, are an indication that no specific diagnostic testing is necessary.

    Treatment Empiric therapy with liberal fluid intake, anti-emetics and antipyretics may suffice. Empiric therapy should only be instituted in immunocompetent patients with symptoms that are mild and typical for a viral syndrome. Signs such as protracted fever with chills, bloody diarrhea and clinically evident fluid depletion should be handled with proper diagnostic studies and appropriate specific therapy.

    A randomized, double-blind comparison of treatment of uncomplicated nausea and vomiting due to viral gastroenteritis with prochorperazine Compazine or promethazine Phernergan was published. The results showed that prochoroperazine was significantly better in terms of symptom relief compared to promethazine These symptoms are generally attributed to the general anesthetic agents or analgesics used.

    In the immediate post-operative setting, these patients are often treated empirically. However, the possibility of other causes of nausea and vomiting must be kept in mind. Vomiting in the post-operative period following laparoscopy may lead to pneumomediastinum and bilateral pneumothoraces Congestion of the eye secondary to phakomorphic glaucoma can lead to intractable nausea and vomiting in the post-operative state Treatment While post-operative nausea and vomiting is unlikely to be encountered in the primary care setting, treatment regimens have been studied in this patient population.

    Therefore, it is useful to be aware of this literature. For example, the efficacy, safety and cost-effectiveness of ondansetron 4 mg intravenously was compared to droperidol 0. In another randomized, double-blind, placebo-controlled trial conducted on patients undergoing laparoscopic cholecystectomy, prophylactic anti-emetic therapy with ondansetron, tropisetron, granisetron or metoclopramide was studied.

    Ondansetron prophylaxis resulted in a lower incidence of post-operative nausea and vomiting compared to metoclopramide or placebo. There were no statistically significant differences among the three 5-HT3 receptor antagonists A review of published controlled trials comparing 5-HT3 receptor antagonists to traditional anti-emetic agents including metoclopramide, perphenazine, prochlorperazine, cyclizine and droperidol for prophylaxis of postoperative nausea and vomiting showed the 5-HT3 receptor antagonists to be superior Most causes of acute vomiting are self-limited illnesses, but nausea and vomiting can be symptoms of conditions that require expeditious diagnostic workup and treatment Table 4.

    Guidelines for referral are included in each section. Abdominal pain preceding nausea and vomiting indicates an organic lesion. Pain following vomiting may be due to tenderness of the abdominal musculature, an abdominal wall or esophageal hematoma, especially in patients who are anti-coagulated or esophageal perforation. These symptoms may be accompanied by abdominal bloating or fullness. Often, concomitant substernal chest pain is present, or the patient may give a history of angina pectoris.

    Even in the absence of classic signs and symptoms of myocardial ischemia, the physician must keep an open mind to the possibility of a cardiac source of symptoms. At a minimum, an electrocardiogram should be obtained in such patients.

    Further diagnostic evaluation and therapy depend on the clinical impression. Cardiac enzymes to rule out myocardial infarction and electrocardiographic monitoring may be necessary. Management in consultation with a cardiologist should be considered. The duration, location, quality, radiation and pattern of abdominal pain, and factors that exacerbate or ameliorate the pain, may help distinguish between these possibilities.

    A history of biliary colic or gallstones suggests cholecystitis or gallstone pancreatitis. Pain in the periumbilical area which moves to the right lower quadrant over time classically suggests appendicitis. On physical exam, certain findings are suggestive of a particular diagnosis. Murphy's sign tenderness and inspiratory arrest with palpation in the right upper quadrant of the abdomen may be elicited in acute cholecystitis. Rebound tenderness on abdominal exam suggests peritonitis, and in the context of free air on X-ray, warrants laparotomy.

    In acute pancreatitis, diffuse tenderness to palpation of the abdomen may be elicited, making this diagnosis a difficult one to make on physical findings alone Nausea and vomiting in the context of intra-abdominal inflammation are symptoms that should respond to treatment of the underlying inflammatory process. Referral to a gastroenterologist should be considered in severe cases of pancreatitis, in those whom choledocholithiasis is suspected as a cause of pancreatitis or cholangitis, and in cases where the diagnosis is uncertain.

    For patients with inflammatory bowel disease IBD presenting with nausea and vomiting, symptoms may be due to a flare of IBD or the presence of bowel obstruction see below. Management of IBD with the aid of a gastroenterologist should be considered.

    Referral to a general surgeon is warranted in cases of acute cholecystitis, appendicitis or peritonitis. When abdominal pain precedes nausea and vomiting, obstruction of the GI tract should be strongly considered.

    Gastric outlet obstruction may be due to peptic ulcer disease in the pyloric channel or duodenal bulb, or benign or malignant gastric tumor. Patients may complain of early satiety and bloating.

    Abdominal pain is generally postprandial. Symptoms may be worse after a solid meal compared to a liquid one. These symptoms may be resolved with vomiting as the stomach is decompressed. The volume of gastric contents expelled may be large. The vomitus may be foul-smelling, containing food ingested more than 12 hours previously. Heartburn due to reflux of acidic gastric contents may be a complaint. Physical exam findings include a distended abdomen with tympany and, in some cases, epigastric tenderness.

    A succussion splash heard with the stethoscope after gently rocking the patient from side to side implicates retention of liquid contents in the stomach. Diagnostic tests include upright abdominal X-rays showing an enlarged gas-filled stomach, contrast radiographs and endoscopy. Water soluble contrast X-rays are helpful when a gastric bezoar is suspected, or when a tight stenosis is present.

    Endoscopy is in many cases the procedure of choice, as histologic diagnosis and in some cases therapy can be provided. Referral to a gastroenterologist is appropriate in cases of acute nausea and vomiting suspected to be due to gastric outlet obstruction.

    In the small bowel, a history of prior abdominal surgery may predispose to small bowel obstruction caused by adhesions. Eighty percent of small bowel obstructions are due to post-operative adhesions. Other etiologies include primary or metastatic carcinoma, benign tumor, internal and external hernias and Crohns disease. Less commonly, prior abdominal radiation, intussusception, endometriosis, volvulus and congenital abnormalities can lead to small bowel obstruction.

    The patient can present with intestinal colic, which may be intermittent initially, progressing to sustained abdominal pain centered in the midline of the abdomen at or cephalad to the umbilicus. Vomiting is a cardinal feature, with complete obstruction leading to vomiting of liquid material which may be feculent if the obstruction is in the distal small intestine.

    Physical findings include a distended abdomen; dilated, palpable loops of bowel; and high-pitched, intermittent bowel sounds. An important aspect of the diagnostic evaluation is the differentiation of incomplete from complete small bowel obstruction.

    Complete obstruction should be considered if the patient is not able to pass flatus. Abdominal radiographs supine and upright views should be obtained. Complete obstruction is suggested by dilated loops of small bowel with air-fluid levels without gas in the large bowel.

    In partial obstruction, gas is noted in the colon and rectum, although air-fluid levels and dilated loops of small bowel are present. If the differentiation between partial and complete obstruction is still uncertain, contrast radiography may help differentiate these conditions and rule out a paralytic ileus.

    If the diagnostic evaluation suggests partial obstruction, nasogastric suction and IV fluids should be instituted. Lack of clinical improvement in 48 hours warrants operative treatment. Complete small bowel obstruction is an indication for laparotomy. Resuscitation pre-operatively includes correction of hypoxemia, replacement of intravascular volume and correction of serum electrolyte abnormalities. Metastases to the GI tract can present with abdominal pain and nausea and vomiting. Melanoma and breast cancer can metastasize to the small bowel.

    Therefore a careful drug history, including the use of over-the-counter medications and herbal and non-traditional medications, is mandatory. Establishing a temporal relationship between the institution of a medication and symptoms of nausea and vomiting is highly suggestive. Alternatively, changes in dosing or the addition of a drug to an already lengthy list of medications suggests a drug-related effect. A large number of drugs have nausea and vomiting listed as a potential side effect; indeed, almost any drug can potentially cause these symptoms.

    However, there are certain drugs for which nausea and vomiting is seen in a significant minority of patients. These agents are listed in Table 5 and are described below. Narcotic analgesics such as morphine, which dramatically decrease gut motility, can lead to constipation and GI tract obstruction.

    Prescription and over the counter non-steroidal anti-inflammatory drugs NSAIDs have nausea and less commonly vomiting as a side effect.

    Theophylline and digoxin can cause nausea and vomiting, especially when plasma drug levels are elevated. Nausea and occasionally vomiting has been noted with the selective serotonin reuptake inhibitors.

    Chloroquine causes nausea and vomiting as a side effect both at prescribed doses and in overdose situations. Antibiotics and anti-parasitic agents can cause nausea and vomiting.

    Trimethoprim-sulfamethoxazole is associated with nausea and vomiting. Erythromycin can cause nausea and vomiting; the mechanism may be related to its role as an agonist for the pro-motility hormone motilin. Anti-helminthics such as albendazole and thiabendazole have been associated with nausea and vomiting. The amebicide iodoquinol has nausea and vomiting as a side effect.

    Other drugs which commonly cause nausea and vomiting include estrogens, levodopa, bromocriptine and potassium and iron salts. For the latter two types of agents, gastric irritation may be the mechanism.

    Timolol eye drops can cause severe nausea and vomiting Several prescription drug overdoses presenting with nausea and vomiting have been reported, including isoniazid 33 , misoprostol 34 , colchicine 35 and metronidazole. Cinchonism secondary to quinine toxicity classically presents with nausea, vomiting, and tinnitus. Prolongation of the Q-T interval is often noted This list is not comprehensive; communication with a Regional Poison Control Center for up-to-date management recommendations should be considered.

    In the context of chemotherapy regimens, anti-emetic therapy is often prescribed. While this situation is unlikely to be encountered in the primary care setting, it is important to keep this possibility in mind. In particular, anticipatory nausea and vomiting may develop in a patient who has undergone prior chemotherapy. In a study of 16 adult cancer patients with chemotherapy-induced anticipatory nausea and vomiting, hypnosis was shown to be highly effective In all patients studied, anticipatory nausea and vomiting disappeared.

    The severity of chemotherapy-induced emesis depends on the particular drug used cisplatin is associated with the highest incidence , the dose of the drug and the method of administration Vomiting may be delayed 2 to 5 days after cisplatin administration and may be difficult to control. Nausea and vomiting may also be encountered in the setting of fractionated radiotherapy for malignancy An overview of the treatment of patients with chemotherapy-induced nausea and vomiting is found in the section on drug therapy.

    Mallory-Weiss tears are directly caused by vomiting or retching and can be encountered in the patient who has been drinking alcohol. Acute pancreatitis may be present and leads to nausea, vomiting and abdominal pain. Intracranial hemorrhage secondary to head trauma from a fall in an inebriated patient can cloud the clinical presentation, as increased intracranial pressure can itself be a cause of nausea and vomiting. Alcoholic hepatitis can also present with nausea and vomiting.

    Nausea and vomiting in the patient with a history of alcohol use therefore requires vigilance for these associated conditions. Ancillary diagnostic tests such as chest and abdominal X-rays and a head CT scan may be necessary to rule out the wide variety of associated conditions that can lead to nausea and vomiting in the patient who presents after heavy alcohol consumption Table 7. Exposure to certain environmental toxins can lead to nausea and vomiting as prominent symptoms.

    Carbon monoxide intoxication presents in a non-specific manner. Headache, dizziness, fatigue and nausea and vomiting are common In addition, disturbed judgment and diminished visual acuity may be seen. Cherry-red coloration of the lips or skin is rare. Hyperbaric oxygen 3 atm is recommended for patients who present with neurologic signs or symptoms, EKG changes consistent with ischemia, shock, severe metabolic acidosis and pulmonary edema.

    Acute arsenic poisoning can present with nausea and vomiting Acute fluoride poisoning from a public water system produced a clinical syndrome characterized by nausea, vomiting, diarrhea, abdominal pain and paresthesias Pesticide exposure can present with anxiety, vertigo, nausea, vomiting, tearing and weakness Elemental mercury vapor toxicity presented with nausea, headache, lumbar pain and shortness of breath at rest In each of these examples, nausea and vomiting were present in the majority of cases but the presenting symptom complexes were non-specific.

    Food poisoning due to pre-formed bacterially-derived toxins can present with nausea and vomiting in association with abdominal pain and diarrhea. Staphylococcal food poisoning typically presents with nausea, vomiting, cramping abdominal pain and diarrhea between two and four hours after ingestion of food contaminated by the enterotoxin produced by Staphylococcus aureus. Often, a cluster of cases is identified. The illness is short, rarely lasting more than 24 hours. Vibrio parahemolyticus poisoning is associated with the consumption of raw or improperly refrigerated seafood.

    The incubation period is between 12 and 24 hours, and patients present with explosive watery diarrhea, nausea, vomiting and abdominal cramps. Treatment is supportive, although in protracted cases, antibiotic therapy with tetracycline or ampicillin may be used. Other bacterial causes of food poisoning such as Clostridium perfringens type A and Bacillus cereus cause nausea and vomiting as predominant symptoms in a minority of patients.

    Toxin exposure can occur by consumption of seafood or exposure to marine toxins. Scombroid poisoning by the consumption of spoiled fish of the dark meat varieties can present with skin rash, diarrhea, palpitations, headache, nausea, abdominal cramps, paresthesias, an unusual taste sensation and breathing difficulties.

    Patients respond to anti-histamines as the toxin is histamine 45 , Cigatuera poisoning, seen predominantly in tropical areas, presents with nausea, abdominal pain, vomiting and diarrhea.

    Peripheral neuropathic symptoms are also characteristic, including paresthesias, dental discomfort and confusion of peripheral hot and cold sensation.

    Although not toxins, certain foods can cause hypersensitivity reactions which present with nausea, vomiting, abdominal pain and diarrhea Certain envenomations can present as nausea and vomiting. Spider bites , particularly by the female black widow spider or brown recluse spider, can present with nausea and vomiting.

    Likewise, scorpion stings and snake bites can present with nausea and vomiting. In all of these cases, pain, erythema and swelling at the site of the bite is usually evident.

    Unusual examples of envenomations which present with nausea and vomiting are those due to the bite of the Gila monster 48 and the sting of the Portuguese man-of-war Certain environmental exposures can lead to nausea and vomiting. Heat exhaustion occurs in an unacclimatized person who exercises on a hot day. It results from loss of salt and water, with the patient complaining of headache, nausea, vomiting, dizziness, weakness, irritability, cramps or diaphoresis.

    Therapy consists of rest in a cool environment, and volume repletion with salt-containing solutions. If vomiting is present, IV normal saline may be necessary. High altitude illness can occur in people unacclimatized to altitude who ascend to more than meters in less than days. Acute mountain sickness presents with headache, nausea, vomiting, anorexia, dyspnea, lethargy, sleep disturbance, vertigo, palpitations and difficulty concentrating.

    In the third trimester of a normal pregnancy, the incidence of nausea and vomiting decreases If nausea and vomiting in the pregnant woman does not fit this typical pattern, then the following conditions should be considered.

    If symptoms are severe, or begin in the second or third trimester, then other more serious conditions need to be considered. Onset of symptoms is often soon after the first missed menstrual period. Classically the vomiting disappears during the third month, and rarely persists into the fourth month. Patients with hyperemesis gravidarum do not have an increased incidence of toxemia of pregnancy or spontaneous abortion, and their babies are not underweight or otherwise affected. In one study, however, intrauterine growth retardation in patients with hyperemesis gravidarum was reported Women with twins or with molar pregnancy hydatidiform mole have an increased incidence of hyperemesis gravidarum.

    These women have elevated concentrations of human chorionic gonadotropin HCG. Abnormalities of thyroid function tests are also common. The metabolic consequences of hyperemesis gravidarum can be severe due to dehydration and muscle wasting, with mortality increased in untreated patients. Gastric emptying is not delayed in patients with hyperemesis gravidarum, suggesting that the disorder is not due to an upper GI tract motility disturbance Treatment Treatment is directed at fluid and electrolyte replacement and supportive psychotherapy Parenteral nutritional therapy may be necessary.

    Standard anti-emetics are generally not effective. Successful management with intravenous hydrocortisone, followed by oral prednisolone has been described in a series of seven patients The combination of intravenous droperidol and diphenhydramine was shown to improve symptoms A placebo-controlled, randomized single-blind study of manual acupressure for the treatment of hypermesis gravidarum performed in 33 women showed that nausea and vomiting was reduced in the acupressure group compared to the placebo group Symptoms of nausea, vomiting, headache and malaise begin in the third trimester, usually around week Features of pre-eclampsia hypertension, edema, proteinuria may be present.

    The disease often progresses to hepatic failure complicated by disseminated intravascular coagulation. Elevated aminotransferases in the range is an indication for liver biopsy. The characteristic finding on biopsy is microvesicular fat. Maternal morbidity is high, and the condition should be suspected in patients with symptoms of pre-eclampsia with hypoglycemia, low fibrinogen and prolonged prothrombin time Treatment Once this diagnosis is established, early delivery is indicated to prevent maternal and fetal death Management by an obstetrician, and referral to a center specializing in high-risk obstetrics should be considered.

    Patients typically present in the third trimester with epigastric or right upper quadrant pain and nausea and vomiting. They may present with no signs of pre-eclampsia hypertension, proteinuria, or edema , and therefore a non-obstetric diagnosis may be entertained Treatment Management in conjunction with an obstetrician is recommended, and referral to a center specializing in high-risk obstetrics should be considered.

    Headache may be due to migraine , increased intracranial pressure or cerebral vascular hemorrhage. The clinical diagnosis of migraine is based on headache characteristics and associated symptoms, particularly nausea and vomiting. The treatment of migraine has been recently reviewed Treatment strategies include 5-hydroxytryptamine agonists, ergotamine tartrate, sumatriptan, dihydroergotamine, NSAIDs and opiates.

    Sumatriptan, a selective serotonin receptor agonist, is particularly effective and well-tolerated 58 Treatment with oral sumatriptan has been studied in a randomized double-blind placebo-controlled study , and found to be effective Headache in the presence of fever and neck stiffness suggests meningitis Nausea and vomiting may be a feature of meningitis.

    Cerebral cysticercosis can present with positional headache and nausea and vomiting 62 Seat vibration however, was shown by the study to have little impact in reducing motion sickness. Autonomous vehicles, at present, may drive in a slightly more jerky way compared with human drivers, since their priority is safety.

    Frequent braking may elevate the feeling of car sickness in sensitive riders. Earlier on Monday, Uber announced that it was planning to buy up to 24, self-driving cars from Volvo. This means you could see a flood of Uber-owned driverless vehicles filling up your streets within the next few years.

    There's no telling whether these patents will actually be commercialised and put into action — most are unlikely to ever see the light of day. But what it does show is that Uber's really trying to perfect the driverless experience. Avoid greasy or acidic foods. Avoid heavy, greasy, and acidic foods in the hours before you travel. Better choices include breads, cereals, grains, milk, water, apple juice, apples, or bananas.

    Do not skip eating but do not overeat. Drink plenty of water to keep your mouth moist and urine light in color. Do not drink large amounts of alcohol the evening before you travel. Alcohol speeds up dehydration and generally lowers your body's resistance to motion sickness, if you are prone to it. Stand if you feel queasy. Stand up, if you can, and look out over the horizon. Despite what you might think, sitting or lying down actually may make you feel worse.

    Don't smoke and avoid others who smoke. Dry crackers may help settle a queasy stomach. Use the seat head rest. Lean your head against the back of the seat or head rest when traveling in vehicles with seats to minimize head movements. Avoid others who have become nauseous with motion sickness. Seeing and smelling others who have motion sickness may cause you to become sick. How is motion sickness treated? Motion sickness can be treated with over-the-counter and prescription drug products. Antihistamines are commonly used both to prevent and treat motion sickness.

    The side effect of these medications is drowsiness. Meclizine is much less sedating, making it a preferred treatment. The patch formulation is applied to the skin area behind the ear and can help prevent motion sickness for up to three days per patch. Scopolamine may create an annoying dry mouth side effect.

    Motion sickness, nausea and thermoregulation: The “toxic” hypothesis

    Jan 12, Don't let motion sickness get the best of you. Associates, P.C., says that sitting facing forward might help to diminish the conflicting signals. Jul 20, To understand how CBD oil helps relieve motion sickness, we need to take a closer look at the Diminish Motion Sickness By Elevating. Feb 23, Motion sickness — an inner ear disorder that causes nausea, but fortunately, there are ways to reduce the chances of it hitting you,” she said.

    Motion Sickness Remedies



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