First and last line on this plate demonstrate a CBD:THC ratio. For more valid information about CBD:THC ratio, please consult these other informative. What do CBD to THC ratios mean and what can they really do? Care by Design, and other companies like Pure Ratios in San Diego, use. The optimal dose involves the right ratio of CBD to THC in the right quantity for CBD:THC ratios, different modes of administration, and potential side effects.
Ratios Different CBD:THC
With the legality of marijuana spreading across the United States and other countries, many people are now being given the opportunity to switch from dangerous, addictive medications to a natural, safer alternative. Whether you are suffering from chronic nerve or body pain, or you are experiencing short-term pain from muscle strain, headaches, toothaches, or simply sore muscles, cannabis offers a safer and possibly more effective option than what is typically used for pain today.
Throughout this time, the cannabis plant has been exalted as miraculous and cursed as a danger to the fabric of society. Yet, throughout this varied past, one thing has remained the same: Cannabis has been used as a plant medicine for the treatment of an impressively wide array of diseases. The earliest evidence of its medicinal use dates back to BC when Chinese Emperor Shen Nung documented the analgesic pain-relieving properties.
Shen Nung is considered by many to be the father of Chinese medicine, which has helped to heal people through the use of natural remedies for thousands of years.
We have now entered a time where the benefits of this plant are beginning to come back to the forefront of the discussion.
Indeed, countless individuals across the world have access to legal marijuana for chronic pain conditions. Should patients turn to singular compounds found in the plant, or turn to the plant itself? If using the whole plant, what marijuana strains are the best for providing relief from pain? When you compare Western medicine to traditional medicine the world over, one of the most striking differences is the need in the West to pinpoint one specific molecule that is responsible for treating a disease or symptom.
This viewpoint stands contrary to the idea of holistic medicine, where you take something in its entirety for medicinal purposes. The Cannabis sativa plant is one of the greatest present-day examples of this tug-of-war between Western medicine and traditional medicine. It has been found to have a variety of health-related benefits for the user. CBD is the second most well-known cannabinoid found in cannabis, and like most of the other phytocannabinoids, it is non-psychotropic.
These are the two most abundant and well-studied cannabinoids in marijuana, and both have been found in numerous published studies to have pain-relieving properties in humans. While they may be the most abundant, THC and CBD are certainly not the only compounds found in cannabis that are known to exert positive effects on human health. In every cannabis plant, there is a unique mixture of hundreds of plant compounds, comprised of phytocannabinoids, terpenes, and flavonoids.
Research suggests that these compounds too have an influence on our neurochemistry, and together they may work synergistically, producing better improvements in pain relief than anyone would produce on its own.
This research supports the idea that it is best to use the whole cannabis plant, with CBD, THC, and the natural medley of additional compounds. This harmony between the various plant chemicals found in marijuana is colloquially referred to as the entourage effect.
The most well-studied compounds found in the marijuana plant that support the idea of the entourage effect are THC and CBD, which have been found to work differently together than when separate. Using these two compounds in concert has been shown to help mitigate side effects and enhance efficacy, with CBD plus THC showing more benefit for some conditions than THC alone. It has also been found to extend the half-life of THC, which may help to extend the pain-relieving benefits.
This has allowed the use of higher doses of THC in clinical trials for the treatment of pain caused by multiple sclerosis, peripheral neuropathic pain, intractable cancer pain, and rheumatoid arthritis. When used in concert, a greater efficacy in treating these types of pain have been observed.
Every strain of bud that you can purchase at a dispensary will be labeled with its THC and CBD content, which can be helpful when choosing which strain to choose for pain relief. CBD has been found to exhibit enhancements in treating pain both when used on its own and when used in combination with THC. When used alone, CBD is largely best for inflammatory pain, such as that caused by arthritis or injuries.
In one animal study on arthritis pain, it was found that the topical application of CBD led to a reduction in inflammation and pain. Another animal study found that CBD helps to reduce neuropathic pain through the suppression of chronic inflammation.
CBD does not directly bind to the receptors found in the endocannabinoid system but rather works to modulate the effects of the endocannabinoids the cannabinoids found naturally in our bodies as well as working as a CB1 receptor antagonist. The main mechanism by which CBD is thought to help mediate pain is by reducing inflammation , largely by blocking inflammatory mediators.
It is also believed to potentiate glycine receptors, which help to regulate pain at the spinal level. This suppresses both neuropathic and inflammatory pain.
THC is used clinically for the treatment of pain and studies find it helps relieve central and neuropathic pain. It is also used to help reduce pain in cancer, AIDS, and fibromyalgia patients, for which resistance to other pain treatments have been found.
The mode of action for THC is as a partial CB1 receptor agonist, which means that it will bind to these receptors but not fully which leads to the variability in effects documented when THC is present with other CB1 agonists, antagonists or both. It has been found to impact the serotonergic, dopaminergic, and glutamatergic systems — an action which may contribute to its pain-relieving benefits.
Additionally, THC has been found to act as an anti-inflammatory agent. While human studies have found benefits from the use of THC, CBD, and whole-plant marijuana in relieving pain, much of the evidence for this use comes from user reports and surveys. When searching for the best cannabis strains for pain relief, you will first want to consider how much THC and CBD is found in the strain.
This is because CBD can help to mediate the side effects of THC while also providing additional anti-inflammatory and analgesic properties. One example would be if you are experiencing inflammation, yet you are wanting to go about your day normally, without the psychotropic effects of THC.
Other times you may be in enough pain that you would like something that takes your mind off the pain while also offering pain relief. In one survey , participants reported that indicas helped more than sativas when it came to headaches, joint pain, neuropathy, and spasticity.
Users also reported indicas to be more helpful when it comes to sleep and sedation. Lastly, there are countless user reports on specific strains of weed that have been found to be powerful for relieving pain. While some of these strains are high CBD, indica strains, some strains of weed used for pain do not fall into this category.
It may be that the other cannabinoids, terpenes, and flavonoids have come together in a harmonious balance that leads to strong pain-relieving properties. There are limited studies examining the effect of CBD alone on pain in humans. When it comes to CBD only studies, the majority are preclinical or animal studies. That said, the research conducted thus far, along with countless user reports, suggests that CBD itself may be able to help relieve pain.
Activation of cannabinoid receptors has been linked to the inhibition of pain. The exact mechanisms of action are still being researched, however, CBD has been found to increase the levels of endocannabinoids in the body, specifically anandamide.
It is plausible that this increase in endogenous endocannabinoids could have an impact on pain. Another study suggests that CBD in rats induced suppression of chronic inflammation and neuropathic pain through potentiating glycine receptors.
Here we will examine the limited scientific evidence, along with theories relating to the use of CBD for pain. Neuropathic pain, also known as nerve pain, is a unique type of pain that is caused by injured, dysfunctional, or irritated nerves.
This pain tends to be chronic and severe, and with no known cure or remedy, every individual is left to try numerous strategies to find something that works for them. Some of the most common sources of neuropathy include diabetes, injury, cancer, infections, alcoholism, and autoimmune disorders. In an animal study , researchers found that oral supplementation of CBD led to improvements in neuropathic pain in rats.
Back pain is one of the most common forms of both acute and chronic pain. Acute back pain tends to be caused by an injury, such as by falling or lifting something heavy. Chronic back pain is that which lasts more than three months and is often caused by a ruptured or bulging disc, arthritis, osteoporosis, scoliosis, or nerve pain. Do not operate a vehicle or machinery under the influence of this drug.
There may be health risks associated with consumption of this product. For use only by adults twenty-one and older. Keep out of the reach of children. The subject of CBD ratios has been a hot topic in the cannabis industry for a few years now, and the concept has only gained more interest as cannabis-derived CBD products have become more affordable and more plentiful over the last couple of years. Published research by local neurologist Dr. After reading through clinical trials and other studies pertaining to CBD, it seems apparent that the varying ratios are more of a matter of preference than effectiveness.
Products with a 1: Products with a 2: This ratio may not be ideal for people who are sensitive to THC, but it's still worth experimenting with. Products with a 5:
Best Marijuana for Pain Relief: CBD or THC Strains?
Because we make products in five CBD-to-THC ratios, we get questions all the helpful for stress, mood elevation, and other mood disorders. At Humboldt Apothecary, we offer a wide variety of different CBD:THC ratios to meet every individual's needs. If you find that the becomes. Wondering what the different CBD:THC ratios are and which is best for you? Read on to learn the best ratios and strains for your needs!.